Asymmetrical flow field-flow fractionation (AF4) technique in pharmaceutical and biomedical applications.
Aree / Gruppi di ricerca
- * Pharmaceutical Technologies
- Group Innovative Pharmaceutical and Cosmetic Technology and Nanotechnology Group (i-PHARCOTEC)
Partecipanti al progetto
- Sapino Simona (Coordinatore/trice)
- Chirio Daniela (Ricercatore/trice)
- Gallarate Marina (Docente)
- Peira Elena (Ricercatore/trice)
Descrizione del progetto
Description:
The field-flow fractionation (FFF) technique has recently emerged in pharmaceutical field as a prominent complement to other size analysis technologies (i.e. size exclusion chromatography, Dynamic Light Scattering, etc.). Fractionation with FFF is gentle and preserves protein/particles structural integrity better than existing alternatives. In the present research project, different nano-systems will be tested in their respective field of application in order to offer integrations between the FFF technique and other methods of physico-chemical characterization. Among the research activities, the international collaboration with Jesus Usón Minimally Invasive Surgery Centre (JUMISC-Spain) concerning the “Characterization and quantification of exosomes by asymmetrical-flow field-flow fractionation” should be mentioned.
Keywords: (i-PHARCOTEC)-Pharmaceutical Technology (SSD CHIM/09)