Members of other units:
Stefano Salmaso (PA, Department of Pharmaceutical & Pharmacological Sciences, University of Padova)
Gianni Durando (National Institute of Metrological Research, Torino , Italy
Sponsors: University of Turin (ex 60%)
Gold nanoparticles have attracted a great deal of attention in recent years because of their enhanced and tunable optical properties, easy production and functionalization as well as their good biocompatibility. Moreover, gold nanoparticles set themselves apart from other nanoplatforms thanks to the unique localized surface plasmon resonance which can be used in the multimodal treatment of cancer, an example of which is photothermal therapy. Gold nanoparticles are then front-runners for use as targeting moieties in external physical trigger based cancer treatment. The aim of this project is to investigate gold nanoparticles in their role as therapeutic ultrasound-responsive agents (nanosonosensitizers) for developing non-invasive anticancer and/or antimicrobial treatments.
Keywords: Gold nanoparticles, therapeutic ultrasound, sonodynamic treatment, cancer, microbial infections