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Evaluation of the efficacy o anti-H1 antihistamine drug(s) for diabetic nephroapthy

Ente finanziatore
Unito Ex-60%
Periodo
Dal 01/01/2017
Coordinatore/trice
Prof.ssa Arianna Carolina Rosa

Aree / Gruppi di ricerca

Partecipanti al progetto

Descrizione del progetto

Members:

Dr. Cristina Grange (Temporary Research Associate, Department of Medical Science and Centre for Molecular Biotechnology, University of Turin, Turin, Italy

Members of other units:
Alessandro Pini (Temporary Researcher, Department of Clinical and Experimental Medicine, University of Florence, Italy)
Paul L. Chazot (Senior Lecturer, School of Biological and Biomedical Sciences and Wolfson Research Institute of Health and Wellbeing, Durham University, Durham, UK)

Sponsors:

Unito Ex 60%

Description:

This project is aimed to investigate the potential efficacy of traditional anti-H1 antihistamine drug(s) as new pharmacological approach in diabetic nephropathy. Specific aims to assess this issue are:

  1. Evaluation of the H1 receptor role in diabetic nephropathy
  2. Evaluation of the pharmacological modulation of the H1 receptor in diabetic nephropathy by bilastine

Expertise in the lab include renal cell culture, in vivo models of diabetes and diabetic nephropathy. Technologies employed include immunobiochemistry and molecular biology.

Keywords: 

Histamine, Histamine receptor, Histamine H4 receptors, Kidney, Diabetes, Diabetic nephropathy

Links:

Ultimo aggiornamento: 08/05/2017 15:36
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