Dipartimento di Scienza e Tecnologia del Farmaco

Prodotti della ricerca

Prodotti della ricerca selezionati

De Silva S, Ocana-Rios I, Cagliero C, Gostel MR, Johnson G, Anderson JL. (2023) Isolation of DNA from plant tissues using a miniaturized matrix solid-phase dispersion approach featuring ionic liquid and magnetic ionic liquid solvents. Analytica chimica acta 1245 340858 [DOI  PMID]

Marengo A, Maciel LS, Cagliero C, Rubiolo P, Herodes K. (2023) Free Amino Acids and Biogenic Amines Profiling and Variation in Wild and Sub-Endemic Cardueae Species from Sardinia and Corse. Plants (Basel, Switzerland) 12(2) [DOI  PMID]

Stilo F, Cialie Rosso M, Squara S, Bicchi C, Cordero C, Cagliero C. (2022) Corylus avellana L. Natural Signature: Chiral Recognition of Selected Informative Components in the Volatilome of High-Quality Hazelnuts. Frontiers in plant science 13 844711 [DOI  PMID]

Emaus MN, Cagliero C, Gostel MR, Johnson G, Anderson JL. (2022) Simple and efficient isolation of plant genomic DNA using magnetic ionic liquids. Plant methods 18(1) 37 [DOI  PMID]

Mastellone G, Marengo A, Sgorbini B, Scaglia F, Capetti F, Gai F, Peiretti PG, Rubiolo P, Cagliero C. (2022) Characterization and Biological Activity of Fiber-Type Cannabis sativa L. Aerial Parts at Different Growth Stages. Plants (Basel, Switzerland) 11(3) [DOI  PMID]

Cagliero C, Bizzo H, Rubiolo P, Marengo A, Galli S, Anderson JL, Sgorbini B, Bicchi C. (2022) Immobilization of phosphonium-based ionic liquid stationary phases extends their operative range to routine applications in the flavor, fragrance and natural product fields. Journal of chromatography. A 1664 462796 [DOI  PMID]

Cagliero C, Bicchi C, Marengo A, Rubiolo P, Sgorbini B. (2022) Gas chromatography of essential oil: State-of-the-art, recent advances, and perspectives. Journal of separation science 45(1) 94-112 [DOI  PMID]

Capetti F, Marengo A, Cagliero C, Liberto E, Bicchi C, Rubiolo P, Sgorbini B. (2021) Adulteration of Essential Oils: A Multitask Issue for Quality Control. Three Case Studies: Lavandula angustifolia Mill., Citrus limon (L.) Osbeck and Melaleuca alternifolia (Maiden & Betche) Cheel. Molecules (Basel, Switzerland) 26(18) [DOI  PMID]

Capetti F, Tacchini M, Marengo A, Cagliero C, Bicchi C, Rubiolo P, Sgorbini B. (2021) Citral-Containing Essential Oils as Potential Tyrosinase Inhibitors: A Bio-Guided Fractionation Approach. Plants (Basel, Switzerland) 10(5) [DOI  PMID]

Cagliero C, Mastellone G, Marengo A, Bicchi C, Sgorbini B, Rubiolo P. (2021) Analytical strategies for in-vivo evaluation of plant volatile emissions - A review. Analytica chimica acta 1147 240-258 [DOI  PMID]

Capetti F, Cagliero C, Marengo A, Bicchi C, Rubiolo P, Sgorbini B. (2020) Bio-Guided Fractionation Driven by In Vitro alpha-Amylase Inhibition Assays of Essential Oils Bearing Specialized Metabolites with Potential Hypoglycemic Activity. Plants (Basel, Switzerland) 9(9) [DOI  PMID]

Acquadro S, Civra A, Cagliero C, Marengo A, Ritta M, Francese R, Sanna C, Bertea C, Sgorbini B, Lembo D, Donalisio M, Rubiolo P. (2020) Punica granatum Leaf Ethanolic Extract and Ellagic Acid as Inhibitors of Zika Virus Infection. Planta medica 86(18) 1363-1374 [DOI  PMID]

Aiello N, Marengo A, Scartezzini F, Fusani P, Sgorbini B, Rubiolo P, Cagliero C. (2020) Evaluation of the Farming Potential of Echinacea Angustifolia DC. Accessions Grown in Italy by Root-Marker Compound Content and Morphological Trait Analyses. Plants (Basel, Switzerland) 9(7) [DOI  PMID]

Mastellone G, Pacheco-Fernandez I, Rubiolo P, Pino V, Cagliero C. (2020) Sustainable Micro-Scale Extraction of Bioactive Phenolic Compounds from Vitis vinifera Leaves with Ionic Liquid-Based Surfactants. Molecules (Basel, Switzerland) 25(13) [DOI  PMID]

Moglia A, Florio FE, Iacopino S, Guerrieri A, Milani AM, Comino C, Barchi L, Marengo A, Cagliero C, Rubiolo P, Toppino L, Rotino GL, Lanteri S, Bassolino L. (2020) Identification of a new R3 MYB type repressor and functional characterization of the members of the MBW transcriptional complex involved in anthocyanin biosynthesis in eggplant (S. melongena L.). PloS one 15(5) e0232986 [DOI  PMID]

Capetti F, Sgorbini B, Cagliero C, Argenziano M, Cavalli R, Milano L, Bicchi C, Rubiolo P. (2020) Melaleuca alternifolia Essential Oil: Evaluation of Skin Permeation and Distribution from Topical Formulations with a Solvent-Free Analytical Method. Planta medica 86(6) 442-450 [DOI  PMID]

Cagliero C, Mazzucotelli M, Rubiolo P, Marengo A, Galli S, Anderson JL, Sgorbini B, Bicchi C. (2020) Can the selectivity of phosphonium based ionic liquids be exploited as stationary phase for routine gas chromatography? A case study: The use of trihexyl(tetradecyl) phosphonium chloride in the flavor, fragrance and natural product fields. Journal of chromatography. A 1619 460969 [DOI  PMID]

Capetti F, Rubiolo P, Bicchi C, Marengo A, Sgorbini B, Cagliero C. (2020) Exploiting the versatility of vacuum-assisted headspace solid-phase microextraction in combination with the selectivity of ionic liquid-based GC stationary phases to discriminate Boswellia spp. resins through their volatile and semivolatile fractions. Journal of separation science 43(9-10) 1879-1889 [DOI  PMID]

Acquadro S, Appleton S, Marengo A, Bicchi C, Sgorbini B, Mandrone M, Gai F, Peiretti PG, Cagliero C, Rubiolo P. (2020) Grapevine Green Pruning Residues as a Promising and Sustainable Source of Bioactive Phenolic Compounds. Molecules (Basel, Switzerland) 25(3) [DOI  PMID]

Ritta M, Marengo A, Civra A, Lembo D, Cagliero C, Kant K, Lal UR, Rubiolo P, Ghosh M, Donalisio M. (2020) Antiviral Activity of a Arisaema Tortuosum Leaf Extract and Some of its Constituents against Herpes Simplex Virus Type 2. Planta medica 86(4) 267-275 [DOI  PMID]

Cagliero C, Bicchi C. (2020) Ionic liquids as gas chromatographic stationary phases: how can they change food and natural product analyses? Analytical and bioanalytical chemistry 412(1) 17-25 [DOI  PMID]

Mazzucotelli M, Minteguiaga MA, Sgorbini B, Sidisky L, Marengo A, Rubiolo P, Bicchi C, Cagliero C. (2020) Ionic liquids as water-compatible GC stationary phases for the analysis of fragrances and essential oils: Quantitative GC-MS analysis of officially-regulated allergens in perfumes. Journal of chromatography. A 1610 460567 [DOI  PMID]

Marengo A, Emaus MN, Bertea CM, Bicchi C, Rubiolo P, Cagliero C, Anderson JL. (2019) Arabidopsis thaliana ITS sequence-specific DNA extraction by ion-tagged oligonucleotides coupled with a magnetic ionic liquid. Analytical and bioanalytical chemistry 411(25) 6583-6590 [DOI  PMID]

Marengo A, Cagliero C, Sgorbini B, Anderson JL, Emaus MN, Bicchi C, Bertea CM, Rubiolo P. (2019) Development of an innovative and sustainable one-step method for rapid plant DNA isolation for targeted PCR using magnetic ionic liquids. Plant methods 15 23 [DOI  PMID]

Marengo A, Maxia A, Sanna C, Mandrone M, Bertea CM, Bicchi C, Sgorbini B, Cagliero C, Rubiolo P. (2019) Intra-specific variation in the little-known Mediterranean plant Ptilostemon casabonae (L.) Greuter analysed through phytochemical and biomolecular markers. Phytochemistry 161 21-27 [DOI  PMID]

Sgorbini B, Cagliero C, Acquadro S, Marengo A, Cordero C, Liberto E, Bicchi C, Rubiolo P. (2019) Evaluation of volatile bioactive secondary metabolites transfer from medicinal and aromatic plants to herbal teas: Comparison of different methods for the determination of transfer rate and human intake. Journal of chromatography. A 1594 173-180 [DOI  PMID]

Sgorbini B, Cagliero C, Liberto E, Rubiolo P, Bicchi C, Cordero C. (2019) Strategies for Accurate Quantitation of Volatiles from Foods and Plant-Origin Materials: A Challenging Task. Journal of agricultural and food chemistry 67(6) 1619-1630 [DOI  PMID]

Mazzucotelli M, Bicchi C, Marengo A, Rubiolo P, Galli S, Anderson JL, Sgorbini B, Cagliero C. (2019) Ionic liquids as stationary phases for gas chromatography-Unusual selectivity of ionic liquids with a phosphonium cation and different anions in the flavor, fragrance and essential oil analyses. Journal of chromatography. A 1583 124-135 [DOI  PMID]

Cagliero C, Bicchi C, Cordero C, Liberto E, Rubiolo P, Sgorbini B. (2018) Ionic liquids as water-compatible GC stationary phases for the analysis of fragrances and essential oils. Analytical and bioanalytical chemistry 410(19) 4657-4668 [DOI  PMID]

Insegnamenti

• Advances in Pharmaceutics
  Dottorato in Scienze Farmaceutiche e Biomolecolari
• Biologia Vegetale (CTF) (FAR0279)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Biologia Vegetale (Tecniche Erboristiche) (FAR0103)
  Corso di Laurea in Tecniche Erboristiche
• Botanicals, alimenti funzionali e integratori alimentari (STF0029)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• LA FILIERA DELLE PIANTE AROMATICHE E MEDICINALI: IDENTITA', ANALISI E SOSTENIBILITA' (STF0081)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Prodotti salutistici: approfondimenti (STF0033)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche

Temi di ricerca

Research activity of Cecilia Cagliero is primarily focused on the development of new technologies for the definition of the composition of volatile and nonvolatile biologically active secondary metabolites of plants and plant products of interest in the pharmaceutical, cosmetic and food fields.

The main topics of research are:

- Characterization of the phytochemical profile and of the biological activity of extracts of plant origin with volatile and nonvolatile secondary metabolites through chromatographic hyphenated techniques (GC-MS, UHPLC-PDA-MS/MS) and in-vitro spectrophotometric assays.

- Development and optimization of sample preparation techniques for the phytochemical characterization of plant samples with new and green phases (in particular ionic liquids and deep eutectic solvents) new extraction methods;

- Development of high and sustainable analytical capacity systems for the GC analysis of samples of vegetable origin and in the fragrance field of medium to high complexity: development of new gas chromatographic stationary phases (e.g. based on ionic liquids) new technologies of gas chromatographic columns (e.g. microfabricated GC columns) and fast-GC methods;

- Enantioselective gas chromatography (Es-GC): development of new cyclodextrin derivatives for GC separation of enantiomers of volatiles of natural origin and in the cosmetic field and study of their thermodynamics of separation; optimization, speeding-up and development of routine applications of enantioselective-GC for the characterization and authentication of matrices of plant origin;

Gruppi di ricerca

• Pharmaceutical Biology and Food Chemistry
• Pharmaceutical Biology (PHYTOCHEM)

Progetti di ricerca

• Essenza del Territorio (OFFICINA AROMATARIA) - CONCLUDED
• Essenza del territorio. Una rete per le vie sabaude dei profumi e dei sapori (LAGNASCO) - CONCLUDED
• EcoFood
• Genepì delle Alpi e altre piante officinali (ALCOTRA-GENEALP)
• Innovazione Tecnologica, Automazione e nuovi Controlli Analitici (ITACA)
• Monitoraggio esposizione a vegetali (POISON)

Attività in agenda

Consulta la mia agenda

Organi

• Commissione Ricerca
• Commissione per l'orientamento, il tutorato e il placement
• Commissione Scarichi inventariali
• Consiglio di Dipartimento

• Commissione Monitoraggio e Riesame del corso di laurea in Chimica e tecnologia farmaceutiche

Ricevimento studenti